Strategies for the Management of Treatment-Resistant Depression

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Strategies for the Management of Treatment-Resistant Depression ~ Member Rate - $25.00

Strategies for the Management of Treatment-Resistant Depression ~ Non-Member Rate - $30.00

Session Summary

Treatment resistant depression (TRD) has gotten increased attention given the higher than anticipated incidence demonstrated by the STAR*D trial and the availability of novel pharmacological and other somatic therapies. The difficulties in addressing TRD are magnified by a high incidence of misdiagnosis. The primary sources for misdiagnoses are inadequate treatment, missed diagnoses of bipolarity or psychosis and medical co-morbidities. Approaches to improve differential diagnosis will be discussed.

Pharmacological interventions for various levels of treatment resistance include switching and augmentation strategies. Data on switching in antidepressant class and out of class will be reviewed. The mounting data on the use of atypical antidepressants will be discussed along with thyroid, lithium, and modafanil augmentation research.

New devices, Transcranial magnetic stimulation (TMS) and vagus nerve stimulation (VNS) have been approved for use in depression. Their place in the management of TRD will be discussed.

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Faculty Information

Scott Aaronson, MD

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Scott Aaronson, MD
Director of Clinical Research Programs
Associate Medical Director
The Retreat at Sheppard Pratt
Director
Transcranial Magnetic Stimulation Services
Sheppard Pratt Health System
Baltimore, MD

Scott T. Aaronson, MD, is Director of Clinical Research Programs at Sheppard Pratt Health System in Baltimore, Maryland, where he has been responsible for developing a research program dedicated to the development of medications and devices for the treatment of illnesses across the spectrum of psychiatric disorders. He is Principal Investigator for studies in various phases and presentations of affective illness, schizophrenia, and dementia. Dr. Aaronson earned his medical degree from Harvard Medical School in Boston and completed a residency in Psychiatry at McLean Hospital in Belmont, Massachusetts.Dr. Aaronson is board-certified in Psychiatry and Forensic Medicine and he is a member of several professional organizations, including Distinguished Fellowship in the American Psychiatric Association and the Maryland Psychiatric Society. He has written and lectured extensively on the recognition and treatment of depression and bipolar disorder and the use of antipsychotic medication. He is currently working on a book about treatment resistant depression with co-authors Drs. Michael Thase and Linda Carpenter. He has been a valued consultant and speaker for many pharmaceutical and medical device companies. In addition to his research work, Dr. Aaronson is the Associate Medical Director of the Retreat at Sheppard Pratt, the hospital’s premiere treatment unit and Director of Transcranial Magnetic Stimulation services.

Consultant:

Eli Lilly, Neuronetics, Cyberonics

Speakers Bureau/Educational Services:

Eli Lilly, AstraZeneca, Neuronetics

Learning Objectives

Recognize the definitions and clinical challenges of managing treatment-resistant depression.
Compare the pharmacologic agents that have shown to be efficacious in treatment-resistant depression.
Outline the recent advances in non-pharmacologic strategies to manage treatment-resistant depression.

Continuing Education Credit

Activity Dates: 04/19/2010 - 04/19/2013
ACPE Contact Hours: 1.0
ACPE Number: 0284-0000-10-007-H01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE and ACCME credit is accepted for certification renewal.

View complete continuing education credit details

ACPE The College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This self-study course provides 1.0 contact hours (0.10 CEUs) of knowledge-based continuing education credit from CPNP approved programming. The ACPE universal program number assigned to this course is 0284-0000-10-007-L01-P (1.0 contact hours).

ACPE approved contact hours are accepted for ANCC Certification Renewal (see pages 5 and 6): At least 50% (37.5 hours) of your 75 continuing education hours must be formally approved continuing education hours. Formally approved continuing education hours meet one or more of the criteria listed below:

Continuing nursing education (CNE) approved for nursing contact hours by an accredited provider or approver of nursing continuing education
Continuing medical education (CME) approved for CME hours
Sponsored by organizations, agencies, or educational institutions accredited or approved by the American Nurses Credentialing Center (ANCC) or the Accreditation Council for Continuing Medical Education (ACCME) or the Accreditation Council for Pharmacy Education (ACPE) or the Commission on Dietetic Registration

Course Requirements

This course is provided online at cpnp.org and consists of the speaker audio and slides. A PDF file of the slides is also provided and access is available to participants indefinitely although ACPE credit is available only through the course expiration date.

Participants in this course must complete an examination and achieve a score of 60% or greater. Successful completion of the course also requires the completion of a course evaluation. ACPE statements of credit can be retrieved by participants online at cpnp.org immediately upon successful completion of the course.

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Recommended:

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Windows XP/2000/Vista and Mac OS 10.4 or better
512MB of RAM for Windows XP or Mac OS
1GB of RAM for Windows Vista

Target Audience

If you are a pharmacist, nurse practitioner or other healthcare professional involved in the medication therapy management of psychiatric and/or neurological patients, we invite you to participate in this online course.

Grant Support

This programming was supported in part by grants from Bristol-Myers Squibb, Otsuka America Pharmaceutical, Inc., Lilly USA, LLC, AstraZeneca and Cyberonics.