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Tafreshi J, Hoang TM, Grigorian T, Pai AD, Tafreshi AR, Pai RG. Impact of iatrogenic, excessive, nondietary sodium administration in patients with acute heart failure exacerbation on hospital length of stay. Pharmacotherapy. 2011;31(1):58-61. doi:10.1592/phco.31.1.58.
STUDY OBJECTIVE: To investigate the sources and quantities of nondietary sodium administration in patients hospitalized for acute heart failure exacerbation, and to evaluate the impact of sodium administration on length of stay. DESIGN: Retrospective analysis. SETTING: University-affiliated medical center. PATIENTS: One hundred and eighty-two consecutive patients admitted to a cardiac intensive care unit for acute heart failure exacerbation between January 1 and June 30, 2009. MEASUREMENTS AND MAIN...
Jarkowski A, Glode AE, Spangenthal EJ, Wong MKK. Heart failure caused by molecularly targeted therapies for cancer. Pharmacotherapy. 2011;31(1):62-75. doi:10.1592/phco.31.1.62.
Cancer therapeutics is undergoing a revolution with the advent of new drugs that can selectively target molecules responsible for carcinogenesis and tumor growth. The type and mechanism of these targeting drugs vary. Some are small molecules that specifically target a binding site on a receptor or signal transduction molecule. Antibodies have been engineered to bind to the receptors or the corresponding ligands that mediate a critical cancer activity. In almost all cases, the intent is to inhibit or shut...
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