Childhood Adversity Increases Risk for Nicotine Dependence and Interacts with α5 Nicotinic Acetylcholine Receptor Genotype Specifically in Males

Source: Neuropsychopharmacology

Childhood Adversity Increases Risk for Nicotine Dependence and Interacts with α5 Nicotinic Acetylcholine Receptor Genotype Specifically in Males

Neuropsychopharmacology 37,
669 (February 2012). doi:10.1038/npp.2011.240

Authors: Pingxing Xie, Henry R Kranzler, Huiping Zhang, David Oslin, Raymond F Anton, Lindsay A Farrer
& Joel Gelernter

Keywords: acetylcholine; addiction & substance abuse; neurogenetics; psychiatry & behavioral sciences; CHRNA5; childhood adversity; gene–environment interaction; nicotine dependence; Fagerstrom test for nicotine dependence score

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