Antidepressants

Pregnancy Outcome After Exposure to Antidepressants and the Role of Maternal Depression: Results From the Norwegian Mother and Child Cohort Study

Abstract: Results of previous studies on the safety of antidepressants during pregnancy have been conflicting. The primary objective of this study was to investigate whether first-trimester exposure to antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs), was associated with increased risk of congenital malformations. The secondary objective was to examine the effects of exposure to antidepressants during pregnancy on birth weight and gestational age.
We included 63,395 women from the Norwegian Mother and Child Cohort Study.

Combination of Antidepressants in the Treatment of Major Depressive Disorder: A Systematic Review and Meta-Analysis

Abstract: The objective was to perform a systematic review and meta-analysis of studies that assessed the effect of the combination of antidepressants from the beginning of the treatment of major depressive disorder. Studies were retrieved from PubMed (1966 to August 2010), Cochrane Library (August 2010), Embase (1980 to August 2010), PsycINFO (1980 to August 2010), Lilacs (1982 to August 2010), clinical trials registry, thesis database (www.capes.gov.br ), and secondary references.

Pretreatment cerebral metabolic activity correlates with antidepressant efficacy of vagus nerve stimulation in treatment-resistant major depression: A potential marker for response?

Publication year: 2012Source:Journal of Affective DisordersCharles R. Conway, John T. Chibnall, Sunil Gangwani, Mark A. Mintun, Joseph L. Price, Tamara Hershey, Luis A. Giuffra, Richard D. Bucholz, Jon J. Christensen, Yvette I. Sheline

The effect of adding psychodynamic therapy to antidepressants in patients with major depressive disorder. A systematic review of randomized clinical trials with meta-analyses and trial sequential analyses

Publication year: 2012Source:Journal of Affective Disorders, Volume 137, Issues 1–3Janus Christian Jakobsen, Jane Lindschou Hansen, Erik Simonsen, Christian Gluud

The Oxford Questionnaire on the Emotional Side-effects of Antidepressants (OQuESA): Development, validity, reliability and sensitivity to change

Publication year: 2012Source:Journal of Affective DisordersJonathan Price, Victoria Cole, Helen Doll, Guy M. Goodwin

Does differential drop-out explain the influence of study design on antidepressant response? A meta-analysis

Publication year: 2012Source:Journal of Affective DisordersBret R. Rutherford, Joel R. Sneed, Steven P. Roose

Discontinuation of antidepressants in people with dementia and neuropsychiatric symptoms (DESEP study): double blind, randomised, parallel group, placebo controlled trial

Objective To determine the effect of discontinuing antidepressant treatment in people with dementia and neuropsychiatric symptoms.

Azilect and an Antidepressant

Hello~   Has anyone had a positive/safe experience with Azilect ( rasagiline ) plus a specific antidepressant in an elderly patient?  Bupropion, perhaps? or Citalopram </=20mg per day Sertraline 100mg Paroxetine 30mg  ...

Quite a bit of psych related updates in today's ASHP update

Hello all! Thought I would share in case some of you missed these updates. Enjoy and Happy Tuesday! Andy ---------- Forwarded message ---------- From: ashp_daily_briefing < ashp_daily_briefing@ashp.custombriefings.com > Date: Tue, Mar ...

Pretreatment cerebral metabolic activity correlates with antidepressant efficacy of vagus nerve stimulation in treatment-resistant major depression: A potential marker for response?

Publication year: 2012Source: Journal of Affective Disorders, Available online 5 March 2012Charles R. Conway, John T. Chibnall, Sunil Gangwani, Mark A. Mintun, Joseph L. Price, ...