Diabetes

Dipeptidyl peptidase-4 inhibitors for treatment of type 2 diabetes mellitus in the clinical setting: systematic review and meta-analysis

Objective To assess the efficacy and safety of dipeptidyl peptidase-4 (DPP-4) inhibitors compared with metformin as monotherapy, or with other commonly used hypoglycaemic drugs combined with...

Cost effectiveness of strategies to combat cardiovascular disease, diabetes, and tobacco use in sub-Saharan Africa and South East Asia: mathematical modelling study

Objective To determine the relative costs and health effects of interventions to combat cardiovascular disease, diabetes, and tobacco related disease in order to guide the allocation of resources in...

A woman with ketoacidosis but not diabetes

A 41 year old woman presented with a one day history of abdominal pain and vomiting. She had been drinking alcohol and three to four bottles of Iso-Gel (isopropanol) a day for the past two weeks.

[Review] Diabetes, hyperglycaemia, and acute ischaemic stroke

Diabetes and ischaemic stroke often arise together. People with diabetes have more than double the risk of ischaemic stroke after correction for other risk factors, relative to individuals without diabetes. Multifactorial treatment of risk factors for stroke—in particular, lifestyle factors, hypertension, and dyslipidaemia—will prevent a substantial number of these disabling strokes. Hyperglycaemia occurs in 30–40% of patients with acute ischaemic stroke, also in individuals without a known history of diabetes.

Incidence of diabetic retinopathy in people with type 2 diabetes mellitus attending the Diabetic Retinopathy Screening Service for Wales: retrospective analysis

In the full online version of this paper by R L Thomas and colleagues (BMJ 2012;344:e874; doi:10.1136/bmj.e874) the name of the fourth author should have been spelt “S Roy Chowdhury” [not “Chowdury”].

Utility of GLP-1R agonists in diabetes requires long term study

What is the clinical relevance to diabetes treatment of the meta-analysis of the effects of glucagon-like peptide-1 receptor (GLP-1R) agonists on weight loss, given that it included mostly short term...

Incidence of diabetic retinopathy in people with type 2 diabetes mellitus attending the Diabetic Retinopathy Screening Service for Wales: retrospective analysis

Objectives To determine the incidence of any and referable diabetic retinopathy in people with type 2 diabetes mellitus attending an annual screening service for retinopathy and whose first screening...

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