diagnosis
Research aims for better diagnosis of language impairments
Recent studies aim at finding better ways to diagnose young children with language impairments. The work could lead to better treatments for individual children with communication disorders.
Prevalence and correlates of the proposed DSM-5 diagnosis of Chronic Depressive Disorder
Publication year: 2012Source:Journal of Affective DisordersJenifer A. Murphy, Gerard J. Byrne
Are there specific neuropsychological deficits underlying poor insight in first episode psychosis?
Publication year: 2012Source:Schizophrenia Research, Volume 135, Issues 1–3Benjamin D.R. Wiffen, Jennifer A. O'Connor, Manuela Russo, Javier D. Lopez-Morinigo, Laura Ferraro, Lucia Sideli, Rowena Handley, Anthony S. David
Next-generation DNA sequencing to improve diagnosis for muscular dystrophy
Scientists have used a revolutionary new DNA-reading technology for a research project that could lead to correct genetic diagnosis for muscle-wasting diseases. The technique could be used to offer people with muscular dystrophy, or a related neuromuscular condition, a more accurate prognosis, which would enable them to make more informed choices on life decisions, including family planning.
Prevalence and correlates of the proposed DSM-5 diagnosis of Chronic Depressive Disorder
Publication year: 2012Source: Journal of Affective Disorders, Available online 3 March 2012Jenifer A. Murphy, Gerard J. Byrne
Q&A: On Early Diagnosis of Schizophrenia
Does an early diagnosis of schizophrenia really make a clinical difference?
Serologic diagnosis of NMO: A multicenter comparison of aquaporin-4-IgG assays
Objectives:
Neuromyelitis optica (NMO) immunoglobulin G (IgG) (aquaporin-4 [AQP4] IgG) is highly specific for NMO and related disorders, and autoantibody detection has become an essential investigation in patients with demyelinating disease. However, although different techniques are now used, no multicenter comparisons have been performed. This study compares the sensitivity and specificity of different assays, including an in-house flow cytometric assay and 2 commercial assays (ELISA and transfected cell-based assay [CBA]).
[Correspondence] Cost-effectiveness of diagnosis of high blood pressure in primary care
Kate Lovibond and colleagues (Oct 1, p 1219) incorrectly conclude that reclassification of people judged to be hypertensive on blood pressure measurements in the clinic as normotensive by means of ambulatory blood pressure monitoring (ABPM) would reduce misdiagnosis and costs.
[Correspondence] Cost-effectiveness of diagnosis of high blood pressure in primary care – Authors' reply
We thank David Wald and colleagues for their thought-provoking response to our paper. Their hypothesis regarding the possible benefits of a polypill in a traditionally defined normotensive population has yet to be proven. In the meantime, the current paradigm within which hypertension guidelines operate is likely to continue, hence our approach.