dose

Fanapt dose conversion

Hello All,     We had an individual admitted to out inpatient facility on Fanapt 6mg BID.  We do not carry Fanapt and the psychiatrist is reluctant to stop the med abruptly.  Does anyone know of a dose conversion between other ...

Lithium and ACEI interaction

Does anyone have any documentation or references on potential lithium level changes in a patient already stable on an ACEI prior to initiation or dose increases of lithium?  I have several articles mentioning the interaction when an ACEI is added to ...

depakote levels

I received the following from a doc I work with. Wondering if anyone has any thoughts. With non-linear kinetics in mind, it seems quite a substantial change.   I can tell you she should have been at steady state for both doses for > 1 week ...

Drug-Induced Movement Disorders

Jack J. Chen, PharmD, FCCP, BCPS, CGP
Associate Professor
Loma Linda University
Loma Linda, CA

This comprehensive review covers approaches for both the recognition and management of drug-induced movement disorders. Pharmacotherapeutic approaches for treating akathisia, dystonia, Parkinsonism and tardive dyskinesia are explored. The importance of early detection via periodic assessment is discussed.

Significance of Clozapine Blood Levels?

Hello- I got a question today from one of the Doctors at our hospital about a clozapine level he had drawn for a patient. I don't see anything about monitoring clozapine levels in any of our internet resources, so I thought I'd check if anyone had any ...

Course Components

The APNA Endorsed CPNP Psychiatric Pharmacotherapy Review Course includes the following:

Patient Question Regarding Invega Sustenna/ fluphenazine decanoate

Good morning- We have a 40 year old male patient with schizophrenia who recieved Invega Sustenna 234mg last Thursday, but does not want to continue with this medication due to increased agitation. He has been on Prolixin 20mg po qhs since 12/19 without ...

Vitamin D With or Without Calcium Supplementation for Prevention of Cancer and Fractures: An Updated Meta-analysis for the U.S. Preventive Services Task Force

Background:

Studies suggest that vitamin D supplementation may reduce cancer and fracture risks.

Purpose:

To examine the benefits and harms of vitamin D with or without calcium supplementation on clinical outcomes of cancer and fractures in adults.

Data Sources:

English-language studies identified from MEDLINE and the Cochrane Central Register of Controlled Trials through July 2011.

Study Selection:

Randomized, controlled trials (RCTs), prospective cohort studies, and nested case–control studies reporting incidence of or death from cancer and fracture outcomes.

mirtazapine for treatment of RLS???

One of our pain mgmt. docs put a patient on mirtazapine bid for restless leg syndrome.  I find lots of cases of it CAUSING RLS in the literature, but so far nothing on it treating it.  Is anyone aware of this usage?   Hum ...

More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression

Publication year: 2011Source: Journal of Affective Disorders, Available online 12 December 2011Daimei Sasayama, Hiroaki Hori, Toshiya Teraishi, Kotaro Hattori, Miho Ota, ...