fear
Consolidation of Remote Fear Memories Involves Corticotropin-Releasing Hormone (CRH) Receptor Type 1-Mediated Enhancement of AMPA Receptor GluR1 Signaling in the Dentate Gyrus
Consolidation of Remote Fear Memories Involves Corticotropin-Releasing Hormone (CRH) Receptor Type 1-Mediated Enhancement of AMPA Receptor GluR1 Signaling in the Dentate Gyrus
Neuropsychopharmacology 37,
787 (February 2012). doi:10.1038/npp.2011.256
Authors: Christoph K Thoeringer, Kathrin Henes, Matthias Eder, Maik Dahlhoff, Wolfgang Wurst, Florian Holsboer, Jan M Deussing, Sven Moosmang
& Carsten T Wotjak
Risk variant for schizophrenia in the neurogranin gene impacts on hippocampus activation during contextual fear conditioning
Risk variant for schizophrenia in the neurogranin gene impacts on hippocampus activation during contextual fear conditioning
Molecular Psychiatry 16,
1072 (November 2011). doi:10.1038/mp.2011.66
Authors: S T Pohlack, F Nees, M Ruttorf, S H Witt, V Nieratschker, M Rietschel
& H Flor
Lower effective connectivity between amygdala and parietal regions in response to fearful faces in schizophrenia
Publication year: 2011Source: Schizophrenia Research, Available online 22 October 2011Prerona Mukherjee, Heather C. Whalley, James W. McKirdy, Andrew M. McIntosh, Eve C. Johnstone, ...
Seeking answers to treat the fear of childbirth
One of five Norwegian women suffers from a fear of childbirth. This fear increases health risks to mother and child, results in more planned and emergency Caesarean sections and consumes substantial resources at hospitals. Now researchers are looking for the causes.
The political effects of existential fear
Why did the approval ratings of President George W. Bush -- who was perceived as indecisive before September 11, 2001 -- soar over 90 percent after the terrorist attacks? Because Americans were acutely aware of their own deaths.
Neurohypophyseal hormones manipulation modulate social and anxiety-related behavior in zebrafish
Abstract
Rationale
Oxytocin (OT) and arginine-vasopressin (AVP) regulate social behavior in mammals. Zebrafish (Danio rerio) allows higher throughput and ease in studying human brain disorders.
Objectives This study investigated in zebrafish the effect of non-mammalian homologs isotocin (IT) and vasotocin (AVT) in comparison
with OT/AVP on social behavior and fear response to predator.
Fear of childbirth increases likelihood of C-section, study suggests
A new study reveals that fear of childbirth is a predisposing factor for emergency and elective cesarean sections, even after psychological counseling. This may mean a negative experience that lasts a lifetime among the approximately 3 percent of women who in this study were estimated to suffer from excessive fear of childbirth.
The bed nucleus of stria terminalis and the amygdala as targets of antenatal glucocorticoids: implications for fear and anxiety responses
Abstract
Rationale Several human and experimental studies have shown that early life adverse events can shape physical and mental health in adulthood.
Stress or elevated levels of glucocorticoids (GCs) during critical periods of development seem to contribute for the appearance
of neurospyschiatric conditions such as anxiety and depression, albeit the underlying mechanisms remain to be fully elucidated.
Objectives The aim of the present study was to determine the long-term effect of prenatal exposure t
Learning-Induced Changes in mPFC–BLA Connections After Fear Conditioning, Extinction, and Reinstatement of Fear
Learning-Induced Changes in mPFC–BLA Connections After Fear Conditioning, Extinction, and Reinstatement of Fear
Neuropsychopharmacology 36,
2276 (October 2011). doi:10.1038/npp.2011.115
Authors: Rose-Marie Vouimba
& Mouna Maroun
Keywords: learning and memory; plasticity; biological psychiatry; psychiatry and behavioral sciences; fear; prefrontal; extinction; amygdale
Control of fear in the brain decoded: Emotional balance is regulated by molecular factors behind stress response, study finds
When healthy people are faced with threatening situations, they react with a suitable behavioral response and do not descend into a state of either panic or indifference, as is the case, for example, with patients who suffer from anxiety. With the help of genetic studies on mice, scientists in Germany have discovered two opposing neuronal regulatory circuits for the generation and elimination of fear.