History
Interaction between tryptophan hydroxylase I polymorphisms and childhood abuse is associated with increased risk for borderline personality disorder in adulthood
Introduction: Borderline personality disorder (BPD) is a severe disorder with high morbidity and mortality, but unknown etiology. Childhood abuse has been proposed as an etiological factor, but the mechanism by which an abuse history could influence the risk for BPD has not been determined.
Distinct Neurochemical Adaptations Within the Nucleus Accumbens Produced by a History of Self-Administered vs Non-Contingently Administered Intravenous Methamphetamine
Distinct Neurochemical Adaptations Within the Nucleus Accumbens Produced by a History of Self-Administered vs Non-Contingently Administered Intravenous Methamphetamine
Neuropsychopharmacology 37,
707 (February 2012). doi:10.1038/npp.2011.248
Authors: Kevin D Lominac, Arianne D Sacramento, Karen K Szumlinski
& Tod E Kippin
Keywords: addiction & substance abuse; glutamate; dopamine; animal models; methamphetamine; nucleus accumbens; self-administration
Interaction Between FKBP5 and Childhood Trauma and Risk of Aggressive Behavior [Original Article]
Context Childhood trauma may predispose individuals to aggressive behavior, and both childhood trauma and aggressive behavior are associated with hypothalamic-pituitary-adrenal axis dysregulation.
Objective To determine whether there would be an interaction between genetic variation in FKBP5 and childhood trauma in predicting aggressive behavior.
War on Disease: a History of the Lister Institute
The Lister Institute of Preventive Medicine, established as a research institute in 1891, was the first medical research charity in the United Kingdom (www.lister-institute.org.uk/about.html).
[Clinical Picture] Abdominal calcifications
A 63-year-old woman presented with a 30-year history of recurrent epilepsy. She reported no history of abdominal pain or distention. She had no history of tuberculosis. She had worked at a pig farm for 30 years. 25 years before admission, she had had a skin biopsy because of painless subcutaneous nodules, which confirmed a diagnosis of cysticercosis. At that time, she was treated with praziquantel for 10 days. Physical examination on admission showed no remarkable abnormalities. Her tuberculin skin test was negative.
Holocene glacial and climate history of Prince Gustav Channel, northeastern Antarctic Peninsula
Publication year: 2011Source: Quaternary Science Reviews, Available online 12 December 2011Mieke Sterken, Stephen J. Roberts, Dominic A. Hodgson, Wim Vyverman, Andrea L. Balbo, ...
Use of Acetazolamide in Sulfonamide-Allergic Patients With Neurologic Channelopathies [Observation]
Objective To report the safe and successful use of the carbonic anhydrase inhibitor acetazolamide for treatment of patients with episodic ataxia and periodic paralysis who had been denied treatment because of a history of severe allergic reactions to antibiotic sulfonamides.
Design Case reports.
Setting University of Rochester Medical Center, Rochester, New York.
Associations between suicide attempts and elevated bedtime salivary cortisol levels in bipolar disorder
Publication year: 2011Source: Journal of Affective Disorders, Available online 10 December 2011Masoud Kamali, Erika F.H. Saunders, Alan R. Prossin, Christine B. Brucksch, Gloria J. Harrington, ...
Suicide and history of childhood trauma among street youth
Publication year: 2011Source: Journal of Affective Disorders, Available online 6 December 2011Scott E. Hadland, Brandon D.L. Marshall, Thomas Kerr, Jiezhi Qi, Julio S. Montaner, ...