Nicotine
Childhood Adversity Increases Risk for Nicotine Dependence and Interacts with α5 Nicotinic Acetylcholine Receptor Genotype Specifically in Males
Childhood Adversity Increases Risk for Nicotine Dependence and Interacts with α5 Nicotinic Acetylcholine Receptor Genotype Specifically in Males
Neuropsychopharmacology 37,
669 (February 2012). doi:10.1038/npp.2011.240
Authors: Pingxing Xie, Henry R Kranzler, Huiping Zhang, David Oslin, Raymond F Anton, Lindsay A Farrer
& Joel Gelernter
Nicotine patch shows benefits in mild cognitive impairment, study suggests
Using a nicotine patch may help improve mild memory loss in older adults, according to a new study.
Effects of chronic nicotine, nicotine withdrawal and subsequent nicotine challenges on behavioural inhibition in rats
Abstract
Rationale Drug addiction is a chronically relapsing disorder characterised by compulsive drug use and loss of control over drug intake.
Although several theories propose impulsivity as a key component of addiction, the precise nature of this relationship remains
unclear.
Objectives This study aims to investigate the short- and longer-term effects of chronic nicotine administration on behavioural inhibition.
Nicotine Therapy Sampling to Induce Quit Attempts Among Smokers Unmotivated to Quit: A Randomized Clinical Trial [Original Investigation]
Background Rates of smoking cessation have not changed in a decade, accentuating the need for novel approaches to prompt quit attempts.
Chronic Disease Management for Tobacco Dependence: A Randomized, Controlled Trial [Original Investigation]
Background Tobacco dependence disorder is a chronic relapsing condition, yet treatment is delivered in discrete episodes of care that yield disappointing long-term quit rates.
CREB involvement in the regulation of striatal prodynorphin by nicotine
Abstract
Rationale The transcription factor cAMP response element binding (CREB) protein plays a pivotal role in drug-dependent neuronal plasticity.
CREB phosphorylation at Ser133 is enhanced by drugs of abuse, including nicotine. Dynorphin (Dyn) contributes to the addictive
process and its precursor gene prodynorphin (PD) is regulated by CREB.
Nicotine Improves Working Memory Span Capacity in Rats Following Sub-Chronic Ketamine Exposure
Nicotine Improves Working Memory Span Capacity in Rats Following Sub-Chronic Ketamine Exposure
Neuropsychopharmacology 36,
2774 (December 2011). doi:10.1038/npp.2011.224
Authors: Samantha L Rushforth, Thomas Steckler
& Mohammed Shoaib
Keywords: cognition; schizophrenia/antipsychotics; animal models; behavioral science; nicotine
Social Interaction Promotes Nicotine Self-Administration with Olfactogustatory Cues in Adolescent Rats
Social Interaction Promotes Nicotine Self-Administration with Olfactogustatory Cues in Adolescent Rats
Neuropsychopharmacology 36,
2629 (December 2011). doi:10.1038/npp.2011.149
Authors: Hao Chen, Burt M Sharp, Shannon G Matta
& Qingling Wu
Keywords: addiction and substance abuse; behavioral science; animal models; acetylcholine; nicotine; aversion; social interaction; gustation; olfaction