outcomes
Outcomes that matter to patients
There’s no shortage of examples of clinicians and patients being misled by surrogate outcomes. In some cases the results have been catastrophic.
Show us the data: why clinical outcomes matter
Data from the NHS will have a key role in the British government’s plan for national economic recovery.
Diffusion Tensor Imaging in Acute Optic Neuropathies: Predictor of Clinical Outcomes [Original Contribution]
Objective To evaluate directional diffusivities within the optic nerve in a first event of acute optic neuritis to determine whether decreased axial diffusivity (AD) would predict 6-month visual outcome and optic nerve integrity measures.
Design Cohort study.
Setting Academic multiple sclerosis center.
Patients Referred sample of 25 individuals who presented within 31 days after acute visual symptoms consistent with optic neuritis. Visits were scheduled at baseline, 2 weeks, and 1, 3, 6, and 12 months.
Effect of Aspirin on Vascular and Nonvascular Outcomes: Meta-analysis of Randomized Controlled Trials [Review Article]
Background The net benefit of aspirin in prevention of CVD and nonvascular events remains unclear. Our objective was to assess the impact (and safety) of aspirin on vascular and nonvascular outcomes in primary prevention.
Data Sources MEDLINE, Cochrane Library of Clinical Trials (up to June 2011) and unpublished trial data from investigators.
Study Selection Nine randomized placebo-controlled trials with at least 1000 participants each, reporting on cardiovascular disease (CVD), nonvascular outcomes, or death were included.