Schizophrenia

Increasing the clozapine: norclozapine ratio with co-administration of fluvoxamine to enhance efficacy and minimize side effects of clozapine therapy.

Légaré N, Grégoire C-A, De Benedictis L, Dumais A. Increasing the clozapine: norclozapine ratio with co-administration of fluvoxamine to enhance efficacy and minimize side effects of clozapine therapy. Med Hypotheses. 2013;80(6):689-91. DOI: 10.1016/j.mehy.2012.12.024. PubMed PMID: 23490199.

Therapeutic drug monitoring of clozapine in relapse prevention: a five-year prospective study.

Gaertner I, Gaertner HJ, Vonthein R, Dietz K. Therapeutic drug monitoring of clozapine in relapse prevention: a five-year prospective study. J Clin Psychopharmacol. 2001;21(3):305-10. PubMed PMID: 11386494.

Monitoring of plasma clozapine levels and its metabolites in refractory schizophrenic patients.

Liu HC, Chang WH, Wei FC, Lin SK, Lin SK, Jann MW. Monitoring of plasma clozapine levels and its metabolites in refractory schizophrenic patients. Ther Drug Monit. 1996;18(2):200-7. PubMed PMID: 8721285.

Fluvoxamine reduces the clozapine dosage needed in refractory schizophrenic patients.

Lu ML, Lane HY, Chen KP, Jann MW, Su MH, Chang WH. Fluvoxamine reduces the clozapine dosage needed in refractory schizophrenic patients. J Clin Psychiatry. 2000;61(8):594-9. PubMed PMID: 10982203.

Improved efficacy and fewer side effects under clozapine treatment after addition of fluvoxamine.

Szegedi A, Wiesner J, Hiemke C. Improved efficacy and fewer side effects under clozapine treatment after addition of fluvoxamine. J Clin Psychopharmacol. 1995;15(2):141-3. PubMed PMID: 7782489.

Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients.

Carrillo JA, Herraiz AG, Ramos SI, Benítez J. Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients. J Clin Psychopharmacol. 1998;18(4):311-6. PubMed PMID: 9690697.

An inter-ethnic comparison study of clozapine dosage, clinical response and plasma levels.

Ng CH, Chong S-A, Lambert T, Fan A, Hackett LP, Mahendran R, et al. An inter-ethnic comparison study of clozapine dosage, clinical response and plasma levels. Int Clin Psychopharmacol. 2005;20(3):163-8. PubMed PMID: 15812267.

Plasma clozapine concentrations predict clinical response in treatment-resistant schizophrenia.

Potkin SG, Bera R, Gulasekaram B, Costa J, Hayes S, Jin Y, et al. Plasma clozapine concentrations predict clinical response in treatment-resistant schizophrenia. J Clin Psychiatry. 1994;55 Suppl B:133-6. PubMed PMID: 7961557.

Relationship between clinical efficacy and clozapine concentrations in plasma in schizophrenia: effect of smoking.

Hasegawa M, Gutierrez-Esteinou R, Way L, Meltzer HY. Relationship between clinical efficacy and clozapine concentrations in plasma in schizophrenia: effect of smoking. J Clin Psychopharmacol. 1993;13(6):383-90. PubMed PMID: 8120151.

Plasma clozapine levels and clinical response for treatment-refractory schizophrenic patients.

Kronig MH, Munne RA, Szymanski S, Safferman AZ, Pollack S, Cooper T, et al. Plasma clozapine levels and clinical response for treatment-refractory schizophrenic patients. Am J Psychiatry. 1995;152(2):179-82. PubMed PMID: 7840349.