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Activity Date: 04/18/2016

Target Audience

This course is designed for pharmacists, nurse practitioners or other healthcare professionals involved in the comprehensive medication management of psychiatric and/or neurological patients.

Session Summary

Antipsychotics are associated with a variety of side effects and include the potential for hematologic issues and blood dyscrasias. Severe neutropenia (formally agranulocytosis) is the most recognized side effect known to occur with clozapine and for which a rigid system of monitoring in the US has been developed. In addition, some patient populations such as patients of African or Middle Eastern descent are known to have differences in normative data ranges which were largely developed in European populations. Thus, Benign Ethnic Neutropenia patients may be perceived to be at risk but may not necessarily have any risk of hematologic complications. Thus, psychiatric pharmacists many times play a role in the identification and treatment of hematologic issues and a better understanding of risks, rationale for guidelines, population differences and treatment options fulfils a much needed gap. This talk will cover blood dyscrasias and hematologic issues with antipsychotic treatment and then focus on issues related to clozapine and the new guidelines that have recently been implemented.

Course Requirements

To receive ACPE credit for the live session at the Annual Meeting, you must:

  • Sign in (or create a FREE account).
  • Register for this course. (sign in first)
  • Attend and participate in the entire session and reflect upon its teachings.
  • Complete the evaluation at the end of the activity. (sign in first)
  • Provide the necessary details in your profile to ensure correct reporting by CPNP to CPE Monitor. (sign in first)

This course will be provided at the CPNP 2016 Annual Meeting, April 17-20, 2016. Upon successful completion, ACPE credit is reported immediately to CPE Monitor although transcripts can be retrieved by participants online at

Faculty Information and Disclosures

Learning Objectives

  1. Describe the epidemiology, clinical presentation, and consequences of hematological side effects of antipsychotic medications.
  2. Identify and discuss changes to blood monitoring guidelines for clozapine.
  3. Understand the contribution of benign ethnic neutropenia to the risk of hematologic side effects.   
  4. Examine cases of hematologic issues encountered with antipsychotic treatment and discuss treatment options and controversies.

Continuing Education Credit and Disclosures

Activity Date: 04/18/2016
ACPE Contact Hours: 1.0
ACPE Number: 0284-0000-16-025-L01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for certification renewal.

ACPEThe College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This self-study course provides 1.0 contact hours (0.1 CEUs) of knowledge-based continuing education credit from CPNP approved programming. The ACPE universal program number assigned to this course is 0284-0000-16-025-L01-P (1.0 contact hours).