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Activity Dates: 04/24/2020 - 04/24/2023

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Target Audience

This course is designed for pharmacists, nurse practitioners or other health care professionals involved in the comprehensive medication management of psychiatric and/or neurological patients.

Session Summary

Research suggests that although alterations of central monoamines might contribute to the generation of depressive states, they do are not necessarily the primary cause of depression. Treatment resistant depression occurs in at least 15–30% of major depressive disorder cases, and in the post-partum depression population, remission rates remain low. Currently available antidepressants require 4-6 weeks of administration prior to the onset of therapeutic efficacy, during which time patients continue to experience symptoms of depression and suicidal ideation. Recently approved agents with more rapid onset have the potential to have a significant impact on treatment-resistant and post-partum depression.

This session will provide an update on novel antidepressant treatments that are recently available or in development, including the mechanisms of action that are thought to underlie their potential antidepressant effects and practical aspects for safe and effective use.

Course Requirements

You will proceed through the following steps to satisfactorily complete this course:

  • Sign in (or create a FREE account).
  • Register for this course. (sign in first)
  • Review the full content of the activity and reflect upon its teachings.
  • Complete the post-test at the end of the activity no later than the closing activity date. (sign in first)
  • Complete the evaluation at the end of the activity. (sign in first)
  • If necessary, complete the post-test retest no later than the closing activity date. (sign in first)
  • Receive a passing grade (70%).
  • Provide the necessary details in your profile to ensure correct reporting by CPNP to CPE Monitor. (sign in first)

Upon successful completion, ACPE credit is reported within 24 hours to CPE Monitor although transcripts can be retrieved by participants online in their ACPE Transcript.

Faculty Information and Disclosures

M. Lindsey Hedgepeth Kennedy, PharmD

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Learning Objectives

  1. Explain the potential utility of antidepressant medications that do not act on monoamines.
  2. Explore the emerging mechanisms of action and efficacy of novel antidepressants in development or recently approved for use.
  3. Describe the practical use of newly approved antidepressants including place in therapy, access and referral, dosing, monitoring, and follow-up.
  4. Recognize advantages and limitations of novel antidepressants.


Continuing Education Credit and Disclosures

Activity Dates: 04/24/2020 - 04/24/2023
ACPE Contact Hours: 1.0
ACPE Number: 0284-0000-20-024-H01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for certification renewal.

ACPEThe College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.