Activity Dates: 05/16/2019 - 04/09/2022
Migraine headaches are the most common neurologic problem of adults worldwide. Emerging theories on the pathophysiology of migraine pain and other symptoms will guide medication management in the future. One of the potential pathways for prophylaxis involves Calcitonin Gene-Related Peptide (CGRP) modulation. CGRPs represent a new medication management option with a novel mechanism of action for a disease state that hasn’t seen any changes since onabotulinumtoxinA was approved for the treatment of chronic migraine since 2010. Patients and prescribers rely on pharmacists to help select appropriate pharmacotherapy and provide education. Pharmacists should understand the CGRP pathway and the ways it may be modified to prevent migraines. This program will describe the current understanding of the pathophysiology of migraine, possible methods of intervening in this pathophysiology with CGRP modulators, and the potential place for CGRP modifying medications in migraine treatment.
You will proceed through the following steps to satisfactorily complete this course:
Participants in this course must complete an examination and achieve a score of 70% or greater. Successful completion of the course also requires the completion of a course evaluation. Upon successful completion, ACPE credit is reported immediately to CPE Monitor although transcripts can be retrieved by participants online at http://cpnp.org/mycpnp/transcript/acpe.
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Nicole Hahn, PharmD, BCACPView biographical information and disclosures
The College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This course provides 1.0 contact hour of knowledge-based continuing education credit from CPNP approved programming.
Off-Label Use: This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA (see faculty information and disclosures). The opinions expressed in the educational activity do not necessarily represent the views of CPNP and any educational partners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer: Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Presentation-Specific Disclosure: My presentation will include discussion of off-label, experimental, and /or investigational use of drugs or devices: eptinezumab, ubrogepant, rimegepant, atogepant, lasmiditan, carbamazepine, metoprolol, candesartan, lisinopril, venlafaxine, amitriptyline, cyproheptadine
It is the policy of CPNP to ensure independence, balance, objectivity, scientific rigor, and integrity in continuing education activities. Those involved in the development of this continuing education activity have made all reasonable efforts to ensure that information contained herein is accurate in accordance with the latest available scientific knowledge at the time of accreditation of this continuing education activity. Information regarding drugs (e.g., their administration, dosages, contraindications, adverse reactions, interactions, special warnings, and precautions) and drug delivery systems is subject to change, however, and the reader is advised to check the manufacturer’s package insert for information concerning recommended dosage and potential problems or cautions prior to dispensing or administering the drug or using the drug delivery systems.
Fair balance is achieved through ongoing and thorough review of all materials produced by faculty, and all educational and advertising materials produced by supporting organizations, prior to educational offerings. Approval of credit for this continuing education activity does not imply endorsement by CPNP for any product or manufacturer identified.