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Activity Dates: 05/16/2019 - 04/09/2022

Target Audience

This course is designed for pharmacists, nurse practitioners or other health care professionals involved in the comprehensive medication management of psychiatric and/or neurological patients.

Session Summary

Migraine headaches are the most common neurologic problem of adults worldwide. Emerging theories on the pathophysiology of migraine pain and other symptoms will guide medication management in the future. One of the potential pathways for prophylaxis involves Calcitonin Gene-Related Peptide (CGRP) modulation. CGRPs represent a new medication management option with a novel mechanism of action for a disease state that hasn’t seen any changes since onabotulinumtoxinA was approved for the treatment of chronic migraine since 2010. Patients and prescribers rely on pharmacists to help select appropriate pharmacotherapy and provide education.  Pharmacists should understand the CGRP pathway and the ways it may be modified to prevent migraines. This program will describe the current understanding of the pathophysiology of migraine, possible methods of intervening in this pathophysiology with CGRP modulators, and the potential place for CGRP modifying medications in migraine treatment.

Course Requirements

You will proceed through the following steps to satisfactorily complete this course:

  • Sign in (or create a FREE account).
  • Register for this course. (sign in first)
  • Review the full content of the activity and reflect upon its teachings.
  • Complete the post-test at the end of the activity no later than the closing activity date. (sign in first)
  • Complete the evaluation at the end of the activity. (sign in first)
  • If necessary, complete the post-test retest no later than the closing activity date. (sign in first)
  • Receive a passing grade (70%).
  • Provide the necessary details in your profile to ensure correct reporting by CPNP to CPE Monitor. (sign in first)

Participants in this course must complete an examination and achieve a score of 70% or greater. Successful completion of the course also requires the completion of a course evaluation. Upon successful completion, ACPE credit is reported immediately to CPE Monitor although transcripts can be retrieved by participants online at

Faculty Information and Disclosures

Learning Objectives

  1. Describe the trigeminovascular theory of migraine.
  2. Identify potential targets for intervention in the treatment or prevention of migraine, including methods of Calcitonin Gene-Related Peptide (CGRP) modification.
  3. Evaluate the pros and cons of blocking CGRP in migraine patients.
  4. Discuss the potential place in pharmacotherapy for CGRP-modifying medications.

Continuing Education Credit and Disclosures

Activity Dates: 05/16/2019 - 04/09/2022
ACPE Contact Hours: 1.0
ACPE Number: 0284-0000-19-026-H01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for certification renewal.

ACPEThe College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This course provides 1.0 contact hour of knowledge-based continuing education credit from CPNP approved programming.