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Activity Dates: 06/19/2015 - 04/20/2018

Target Audience

This course is designed for pharmacists, nurse practitioners or other healthcare professionals involved in the comprehensive medication management of psychiatric and/or neurological patients.

Session Summary

The CYP450 system is responsible for the metabolism of many psychotropic medications, and is also involved in a plethora of drug-drug interactions. Due to its prominence in drug metabolism and drug-drug interactions, it is the most well-known system of drug metabolism. There are, however, other enzyme systems responsible for drug metabolism, such as those involved in Phase II metabolism, which often get overlooked. These enzyme systems are involved in the metabolism of many psychotropic drugs and each of these enzymes has inducers, inhibitors, and substrates, many of which are psychotropic medications. A good understanding of these enzyme systems are crucial in recognizing potential drug interactions.

Course Requirements

You will proceed through the following steps to satisfactorily complete this course:

  • Review the full content of the activity and reflect upon its teachings.
  • Complete the post-test at the end of the activity no later than the closing activity date. (login first)
  • Complete the evaluation at the end of the activity. (login first)
  • If necessary, complete the post-test retest no later than the closing activity date. (login first)
  • Receive a passing grade (70%).
  • Provide the necessary details in your profile to ensure correct reporting by CPNP to CPE Monitor. (login first)

This course is provided online at cpnp.org and consists of the speaker audio and slides. A PDF file of the slides is also provided and access is available to participants indefinitely although ACPE credit is available only through the course expiration date.

Participants in this course must complete an examination and achieve a score of 70% or greater. Successful completion of the course also requires the completion of a course evaluation. ACPE statements of credit can be retrieved by participants online at cpnp.org immediately upon successful completion of the course.

Faculty Information and Disclosures

Learning Objectives

  1. Describe the non-CYP 450 enzyme systems involved in Phase I and Phase II drug metabolism.
  2. Discuss the role of non-CYP 450 enzyme systems in drug-drug interactions.
  3. Differentiate between substrates, inducers, and inhibitors of non-CYP 450 enzyme systems.
  4. Evaluate a medication regimen for drug-drug interactions involving non-CYP 450 enzyme-dependent metabolism.

Continuing Education Credit and Disclosures

Activity Dates: 06/19/2015 - 04/20/2018
ACPE Contact Hours: 1.0
ACPE Number: 0284-0000-15-010-H01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for certification renewal.

ACPEThe College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This self-study course provides 1.0 contact hours (0.10 CEUs) of knowledge-based continuing education credit from CPNP approved programming. The ACPE universal program number assigned to this course is 0284-0000-15-010-H01-P (1.0 contact hours).