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Activity Dates: 04/20/2010 - 04/20/2013

This course is closed. Please look for other available products in CPNP University.

Target Audience

If you are a pharmacist, nurse practitioner or other healthcare professional involved in the comprehensive medication management of psychiatric and/or neurological patients, we invite you to participate in this online course.

Session Summary

Over 1 million people are living with HIV in the United States. Transmission is on the rise in women, Blacks, Hispanics, heterosexuals, adolescents and elderly. People with human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome have high rates of psychiatric illness. The effective management of these psychiatric conditions can improve a patient's quality of life and may improve antiretroviral adherence.

This session will outline the pathophysiology of HIV and how it relates to the development of psychiatric illnesses, and how psychiatric illness can lead to transmission of HIV. It will review the 3 major treatment challenges involved in HIV patients with psychiatric comorbidities;  1) Correct psychiatric diagnosis, 2) medication treatment, adherence and side effects, and 3) psychotropic and antiretroviral drug interactions.

The most common drug-drug interactions (DDI’s) with antiretrovirals and psychotropics will be described including the many potential interactions based on cytochrome P450 metabolism, which is common to many psychotropics, the protease inhibitors, and the nonnucleoside reverse-transcriptase inhibitors. Case presentations are used to identify the most appropriate treatment and management of DDI’s in HIV patients with psychiatric illnesses. In managing drug interactions, in general the newer psychotropic agents have a lower potential for drug-drug interactions.For psychotropic dosing in HIV patients, low initial doses and slow titration is necessary to prevent adverse effects.As pharmacists, it is important to keep updated on newly approved medications and their interactions. In conclusion, managing psychiatric illness in HIV-infected patients can be a major challenge and is a perfect role for Psychiatric and Neurologic Pharmacists.

Course Requirements

You will proceed through the following steps to satisfactorily complete this course:

  • Review the full content of the activity and reflect upon its teachings.
  • Complete the post-test at the end of the activity no later than the closing activity date. (login first)
  • Complete the evaluation at the end of the activity. (login first)
  • Receive a passing grade (60%).
  • Provide the necessary details in your profile to ensure correct reporting by CPNP to CPE Monitor. (login first)

This course is provided online at cpnp.org and consists of the speaker audio and slides. A PDF file of the slides is also provided and access is available to participants indefinitely although ACPE credit is available only through the course expiration date.

Participants in this course must complete an examination and achieve a score of 60% or greater. Successful completion of the course also requires the completion of a course evaluation. ACPE statements of credit can be retrieved by participants online at cpnp.org immediately upon successful completion of the course.

Faculty Information and Disclosures

Learning Objectives

  1. Outline pathophysiology of HIV and how it relates to the development of psychiatric illnesses (e.g., depression, psychosis).
  2. Indicate the treatment challenges involved in HIV patients with psychiatric comorbidities.
  3. Identify the most common drug-drug interactions (DDIs) with antiretrovirals and psychotropics.
  4. Identify most appropriate treatment and management of DDIs in HIV patients with psychiatric illnesses.

Continuing Education Credit and Disclosures

Activity Dates: 04/20/2010 - 04/20/2013
ACPE Contact Hours: 1.0
ACPE Number: 0284-0000-10-013-H02-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for certification renewal.

ACPEThe College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This self-study course provides 1.0 contact hours (0.10 CEUs) of knowledge-based continuing education credit from CPNP approved programming. The ACPE universal program number assigned to this course is 0284-0000-10-013-L02-P (1.0 contact hours).

ACPE approved contact hours are accepted for ANCC Certification Renewal (see pages 5 and 6): At least 50% (37.5 hours) of your 75 continuing education hours must be formally approved continuing education hours. Formally approved continuing education hours meet one or more of the criteria listed below:

  1. Continuing nursing education (CNE) approved for nursing contact hours by an accredited provider or approver of nursing continuing education
  2. Continuing medical education (CME) approved for CME hours
  3. Sponsored by organizations, agencies, or educational institutions accredited or approved by the American Nurses Credentialing Center (ANCC) or the Accreditation Council for Continuing Medical Education (ACCME) or the Accreditation Council for Pharmacy Education (ACPE) or the Commission on Dietetic Registration

Grant Support

This programming was supported in part by grants from Bristol-Myers Squibb, Otsuka America Pharmaceutical, Inc., Lilly USA, LLC, AstraZeneca and Cyberonics.

Annual Meeting Grant Supporter

This activity is supported by an educational grant from Lilly USA, LLC. For further information concerning Lilly grant funding visit www.lillygrantoffice.com.