A common cause of drug-drug interactions is result of cytochrome P450 metabolism. Several psychotropic agents are significantly impacted by CYP interactions or are found to be the cause of such interactions in CYP450 metabolism.

Essential Questions and References

Is there a list of psychotropic agents and their CYP substrates and inducing/inhibiting capabilities?

  1. CYP450 Drug Interactions Table for Psychiatric Medications. Updated 2017. [Weblink]

Is there a list of CYP substrates and associated medications?

  1. Flockhart DA. Drug Interactions: Cytochrome P450 Drug Interaction Table. Indiana University School of Medicine (2007). Accessed: September 2020. [Weblink]

Where can I find a database with multiple interaction analyses?

  1. Pharmacist's Letter: Cytochrome P450 (CYP) Drug Interactions. Updated 2020. [Weblink]
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