USP General Chapter <800> Compliance Toolkit and Resources for Psychiatric Facilities

The CPNP USP <800> Compliance Toolkit includes assessments of risk on the formulations listed below. To request additional formulations, simply email the CPNP Office, and they will be considered.

  1. Abacavir, Solution
  2. Abacavir, Tablet
  3. Abacavir/Dolutegravir/Lamivudine, Tablet
  4. Abacavir/Lamivudine, Tablet
  5. Abacavir/Lamivudine/Zidovudine, Tablet
  6. Acitretin, Capsule
  7. Anastrozole, Tablet
  8. Azathioprine, Injection
  9. Azathioprine, Tablet
  10. Bexarotene, Capsule
  11. Bicalutamide, Tablet
  12. Cabergoline, Tablet
  13. Capecitabine, Tablet
  14. Carbamazepine, Capsule, XR
  15. Carbamazepine, Suspension
  16. Carbamazepine, Tablet
  17. Carbamazepine, Tablet, Chew
  18. Carbamazepine, Tablet, XR
  19. Clomiphene, Tablet
  20. Clonazepam, Oral Disintegrating Tablet
  21. Clonazepam, Tablet
  22. Colchicine, Capsule
  23. Colchicine, Tablet
  24. Cyclosporine, Capsule
  25. Cyclosporine, Ophthalmic
  26. Cyclosporine, Solution
  27. Dinoprostone, Vaginal Suppository
  28. Divalproex, Sprinkles
  29. Divalproex, Tablet DR & ER
  30. Dronedarone, Tablet
  31. Dutasteride, Capsule
  32. Entecavir, Solution
  33. Entecavir, Tablet
  34. Eslicarbazepine, Tablet
  35. Estradiol, Gel
  36. Estradiol, Patch
  37. Estradiol, Spray, Topical
  38. Estradiol, Tablet
  39. Estradiol, Vaginal Cream
  40. Estradiol, Vaginal Insert
  41. Estrogen/Progestin Combinations, Patch
  42. Estrogen/Progestin Combinations, Tablet
  43. Estrogens, Conjugated, Injection
  44. Estrogens, Conjugated, Tablet
  45. Estrogens, Conjugated, Vaginal Cream
  46. Estropipate, Tablet
  47. Finasteride, Tablet
  48. Fingolimod, Capsule
  49. Fluconazole, IV
  50. Fluconazole, Suspension
  51. Fluconazole, Tablet
  52. Fluorouracil, Cream
  53. Fluorouracil, Solution, Topical
  54. Flutamide, Capsule
  55. Fosphenytoin, IV
  56. Hydroxyurea, Capsule
  57. Hydroxyurea, Tablet
  58. Leflunomide, Tablet
  59. Letrozole, Tablet
  60. Liraglutide Recombinant, Injection
  61. Medroxyprogesterone, Injection
  62. Medroxyprogesterone, Tablet
  63. Megestrol, Liquid
  64. Megestrol, Tablet
  65. Mercaptopurine, Tablet
  66. Methimazole, Tablet
  67. Methotrexate, Solution
  68. Methotrexate, Tablet
  69. Methyltestosterone, Capsule
  70. Methyltestosterone, Tablet
  71. Misoprostol, Tablet
  72. Mycophenolate Mofetil, IV
  73. Mycophenolate Mofetil, Liquid
  74. Mycophenolate Mofetil, Tablet/Capsule
  75. Mycophenolic Acid, Tablet
  76. Nevirapine, Suspension
  77. Nevirapine, Tablet
  78. Nevirapine, Tablet ER
  79. Oxcarbazepine, Suspension
  80. Oxcarbazepine, Tablet
  81. Paroxetine, Suspension
  82. Paroxetine, Tablet
  83. Paroxetine, Tablet ER
  84. Phenytoin, Capsule
  85. Phenytoin, Suspension
  86. Phenytoin, Tablet, Chew
  87. Progesterone, Capsule
  88. Progesterone, Injection
  89. Progesterone, Vaginal Insert & Suppository
  90. Propylthiouracil, Tablet
  91. Raloxifene, Tablet
  92. Ribavirin, Capsule
  93. Ribavirin, Solution
  94. Ribavirin, Tablet
  95. Sirolimus, Solution
  96. Sirolimus, Tablet
  97. Sorafenib, Tablet
  98. Spironolactone, Tablet
  99. Tacrolimus, Capsule
  100. Tacrolimus, Capsule XR/Tablet XR
  101. Tacrolimus, Ointment
  102. Tamoxifen, Solution
  103. Tamoxifen, Tablet
  104. Temazepam, Capsule
  105. Testosterone, Buccal Tablet
  106. Testosterone, Gel/Jelly
  107. Testosterone, Injection
  108. Testosterone, Patch
  109. Testosterone, Solution, Topical
  110. Testosterone, Spray, Topical
  111. Thalidomide, Capsule
  112. Topiramate, Capsule ER/Tablet ER
  113. Topiramate, Sprinkle
  114. Topiramate, Tablet
  115. Tretinoin, Capsule
  116. Tretinoin, Gel/Jelly/Cream
  117. Valganciclovir, Solution
  118. Valganciclovir, Tablet
  119. Valproic Acid/Valproate, Capsule
  120. Valproic Acid/Valproate, Injection
  121. Valproic Acid/Valproate, Suspension
  122. Vigabatrin, Packet, Oral
  123. Vigabatrin, Tablet
  124. Voriconazole, Injection
  125. Voriconazole, Suspension
  126. Voriconazole, Tablet
  127. Warfarin, Tablet
  128. Zidovudine, Capsule
  129. Zidovudine, IV
  130. Zidovudine, Syrup
  131. Zidovudine, Tablet
  132. Ziprasidone, Capsule
  133. Ziprasidone, Injection
  134. Zoledronic Acid, IV
  135. Zonisamide, Capsule

Formulations with Pending Assessments of Risk

To request additional formulations, simply email the CPNP Office, and they will be considered.

We are monitoring the NIOSH 2020 update, but it has yet to be finalized. Once finalized, potential additions to the toolkit include Exenatide, Interferon Beta 1-B, Clobazam, Triazolam, Isotretinoin, and others. While the list remains in draft, these Assessments of Risk will not be developed.

Removed Formulations

The following formulations have been removed from the toolkit due to a change of designation that excludes them from the USP <800> compliance process.

Omitted: Medications NOT Eligible for Assessments of Risk

USP 800 allows an assessment of risk to be completed on all medications on Table 2: Non-antineoplastic Hazardous Drugs and Table 3: Non-antineoplastic Drugs that primarily have adverse reproductive effects. However, for medications on Table 1: Antineoplastic Drugs, an assessment of risk is only allowed if the product is a solid dosage form. For all other medications on Table1: Antineoplastic Drugs, full compliance with all standards in USP 800 is required. Table 1 medications are listed below, but the latest complete list can always be found in the NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings.

  • Abiraterone
  • Ado-trastuzumab emtansine
  • Afatinib
  • Altretamine
  • Amsacrine
  • Anastrozole
  • Arsenic trioxide
  • Axitinib
  • Azacitidine
  • Bacillus calmette guerin (bcg)
  • Belinostat
  • Bendamustine
  • Bexarotene
  • Bacalutimide
  • Bleomycin
  • Bortezomib
  • Bosutinib
  • Brentuximab
  • Vedotin
  • Busulfan
  • Cabazitaxel
  • Cabozantinib
  • Capecitabine
  • Carboplatin
  • Carfilzomib
  • Carmustine
  • Chlorambucil
  • Cisplatin
  • Cladribine
  • Clofarabine
  • Crizotinib
  • Cyclophosphamide
  • Cytarabine
  • Dabrafenib
  • Dacarbazine
  • Dactinomycin
  • Dasatinib
  • Daunorubicin
  • Decitabine
  • Degarelix
  • Docetaxel
  • Doxorubicin
  • Agents
  • Enzalutamide
  • Epirubicin
  • Eribulin
  • Erlotinib
  • Estramustine
  • Etoposide
  • Everolimus
  • Exemestane
  • Floxuridine
  • Fludarabine
  • Fluorouracil
  • Flutamide
  • Fulvestrant
  • Gemcitabine
  • Gemtuzumab ozogamicin
  • Goserelin
  • Histrelin
  • Hydroxyurea
  • Idarubicin
  • Ifosfamide
  • Imatinib
  • Irinotecan
  • Ixazomib
  • Ixabepilone
  • Agents
  • Letrozole
  • Leuprolide
  • Lomustine
  • Mechlorethamine
  • Megestrol
  • Melphalan
  • Mercaptopurine
  • Methotrexate
  • Mitomycin
  • Mitotane
  • Mitoxantrone
  • Nelarabine
  • Nilotinib
  • Omacetaxine
  • Oxaliplatin
  • Paclitaxel
  • Panobinostat
  • Pazopanib
  • Pemetrexed
  • Pentostatin
  • Pertuzumab
  • Pipobroman
  • Pomalidomide
  • Ponatinib
  • Pralatrexate
  • Procarbazine
  • Regorafenib
  • Romidepsin
  • Sorafenib
  • Streptozocin
  • Sunitinib
  • Tamoxifen
  • Temozolomide
  • Temsirolimus
  • Teniposide
  • Thioguanine
  • Thiotepa
  • Topotecan
  • Toremifene
  • Trametinib
  • Trifluridine/tipiracil (combination only)
  • Triptorelin 
  • Valrubicin
  • Vandetanib
  • Vemurafenib
  • Vinblastine
  • Vincristine
  • Vinorelbine
  • Vismodegib
  • Vorinostat
  • Ziv-aflibercept