USP General Chapter <800> Compliance Toolkit and Resources for Psychiatric Facilities

The CPNP USP <800> Compliance Toolkit includes assessments of risk on the formulations listed below. To request additional formulations, simply email the CPNP Office, and they will be considered.

  1. Abacavir, Solution
  2. Abacavir, Tablet
  3. Abacavir/Dolutegravir/Lamivudine, Tablet
  4. Abacavir/Lamivudine, Tablet
  5. Abacavir/Lamivudine/Zidovudine, Tablet
  6. Acitretin, Capsule
  7. Anastrozole, Tablet
  8. Azathioprine, Injection
  9. Azathioprine, Tablet
  10. Bexarotene, Capsule
  11. Bicalutamide, Tablet
  12. Cabergoline, Tablet
  13. Capecitabine, Tablet
  14. Carbamazepine, Capsule, XR
  15. Carbamazepine, Suspension
  16. Carbamazepine, Tablet
  17. Carbamazepine, Tablet, Chew
  18. Carbamazepine, Tablet, XR
  19. Clomiphene, Tablet
  20. Clonazepam, Oral Disintegrating Tablet
  21. Clonazepam, Tablet
  22. Colchicine, Capsule
  23. Colchicine, Tablet
  24. Cyclosporine, Capsule
  25. Cyclosporine, Ophthalmic
  26. Cyclosporine, Solution
  27. Dinoprostone, Vaginal Suppository
  28. Divalproex, Sprinkles
  29. Divalproex, Tablet DR & ER
  30. Dronedarone, Tablet
  31. Dutasteride, Capsule
  32. Entecavir, Solution
  33. Entecavir, Tablet
  34. Estradiol, Gel
  35. Estradiol, Patch
  36. Estradiol, Spray, Topical
  37. Estradiol, Tablet
  38. Estradiol, Vaginal Cream
  39. Estradiol, Vaginal Insert
  40. Estrogen/Progestin Combinations, Patch
  41. Estrogen/Progestin Combinations, Tablet
  42. Estrogens, Conjugated, Injection
  43. Estrogens, Conjugated, Tablet
  44. Estrogens, Conjugated, Vaginal Cream
  45. Estropipate, Tablet
  46. Finasteride, Tablet
  47. Fingolimod, Capsule
  48. Fluconazole, IV
  49. Fluconazole, Suspension
  50. Fluconazole, Tablet
  51. Fluorouracil, Cream
  52. Fluorouracil, Solution, Topical
  53. Flutamide, Capsule
  54. Fosphenytoin, IV
  55. Hydroxyurea, Capsule
  56. Hydroxyurea, Tablet
  57. Leflunomide, Tablet
  58. Letrozole, Tablet
  59. Liraglutide Recombinant, Injection
  60. Medroxyprogesterone, Injection
  61. Medroxyprogesterone, Tablet
  62. Megestrol, Liquid
  63. Megestrol, Tablet
  64. Mercaptopurine, Tablet
  65. Methimazole, Tablet
  66. Methotrexate, Solution
  67. Methotrexate, Tablet
  68. Methyltestosterone, Capsule
  69. Methyltestosterone, Tablet
  70. Misoprostol, Tablet
  71. Mycophenolate Mofetil, IV
  72. Mycophenolate Mofetil, Liquid
  73. Mycophenolate Mofetil, Tablet/Capsule
  74. Mycophenolic Acid, Tablet
  75. Nevirapine, Suspension
  76. Nevirapine, Tablet
  77. Nevirapine, Tablet ER
  78. Oxcarbazepine, Suspension
  79. Oxcarbazepine, Tablet
  80. Paroxetine, Suspension
  81. Paroxetine, Tablet
  82. Paroxetine, Tablet ER
  83. Phenytoin, Capsule
  84. Phenytoin, Suspension
  85. Phenytoin, Tablet, Chew
  86. Progesterone, Capsule
  87. Progesterone, Injection
  88. Progesterone, Vaginal Insert & Suppository
  89. Propylthiouracil, Tablet
  90. Raloxifene, Tablet
  91. Ribavirin, Capsule
  92. Ribavirin, Solution
  93. Ribavirin, Tablet
  94. Sirolimus, Solution
  95. Sirolimus, Tablet
  96. Sorafenib, Tablet
  97. Spironolactone, Tablet
  98. Tacrolimus, Capsule
  99. Tacrolimus, Capsule XR/Tablet XR
  100. Tacrolimus, Ointment
  101. Tamoxifen, Solution
  102. Tamoxifen, Tablet
  103. Temazepam, Capsule
  104. Testosterone, Buccal Tablet
  105. Testosterone, Gel/Jelly
  106. Testosterone, Injection
  107. Testosterone, Patch
  108. Testosterone, Solution, Topical
  109. Testosterone, Spray, Topical
  110. Thalidomide, Capsule
  111. Topiramate, Capsule ER/Tablet ER
  112. Topiramate, Sprinkle
  113. Topiramate, Tablet
  114. Tretinoin, Capsule
  115. Tretinoin, Gel/Jelly/Cream
  116. Valganciclovir, Solution
  117. Valganciclovir, Tablet
  118. Valproic Acid/Valproate, Capsule
  119. Valproic Acid/Valproate, Injection
  120. Valproic Acid/Valproate, Suspension
  121. Vigabatrin, Packet, Oral
  122. Vigabatrin, Tablet
  123. Voriconazole, Injection
  124. Voriconazole, Suspension
  125. Voriconazole, Tablet
  126. Warfarin, Tablet
  127. Zidovudine, Capsule
  128. Zidovudine, IV
  129. Zidovudine, Syrup
  130. Zidovudine, Tablet
  131. Ziprasidone, Capsule
  132. Ziprasidone, Injection
  133. Zoledronic Acid, IV
  134. Zonisamide, Capsule

Formulations with Pending Assessments of Risk

To request additional formulations, simply email the CPNP Office, and they will be considered.

We are monitoring the NIOSH 2020 update, but it has yet to be finalized. Once finalized, potential additions to the toolkit include Exenatide, Interferon Beta 1-B, Clobazam, Triazolam, Isotretinoin, and others. While the list remains in draft, these Assessments of Risk will not be developed.

Removed Formulations

The following formulations have been removed from the toolkit due to a change of designation that excludes them from the USP <800> compliance process.

Omitted: Medications NOT Eligible for Assessments of Risk

USP 800 allows an assessment of risk to be completed on all medications on Table 2: Non-antineoplastic Hazardous Drugs and Table 3: Non-antineoplastic Drugs that primarily have adverse reproductive effects. However, for medications on Table 1: Antineoplastic Drugs, an assessment of risk is only allowed if the product is a solid dosage form. For all other medications on Table1: Antineoplastic Drugs, full compliance with all standards in USP 800 is required. Table 1 medications are listed below, but the latest complete list can always be found in the NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings.

  • Abiraterone
  • Ado-trastuzumab emtansine
  • Afatinib
  • Altretamine
  • Amsacrine
  • Anastrozole
  • Arsenic trioxide
  • Axitinib
  • Azacitidine
  • Bacillus calmette guerin (bcg)
  • Belinostat
  • Bendamustine
  • Bexarotene
  • Bacalutimide
  • Bleomycin
  • Bortezomib
  • Bosutinib
  • Brentuximab
  • Vedotin
  • Busulfan
  • Cabazitaxel
  • Cabozantinib
  • Capecitabine
  • Carboplatin
  • Carfilzomib
  • Carmustine
  • Chlorambucil
  • Cisplatin
  • Cladribine
  • Clofarabine
  • Crizotinib
  • Cyclophosphamide
  • Cytarabine
  • Dabrafenib
  • Dacarbazine
  • Dactinomycin
  • Dasatinib
  • Daunorubicin
  • Decitabine
  • Degarelix
  • Docetaxel
  • Doxorubicin
  • Agents
  • Enzalutamide
  • Epirubicin
  • Eribulin
  • Erlotinib
  • Estramustine
  • Etoposide
  • Everolimus
  • Exemestane
  • Floxuridine
  • Fludarabine
  • Fluorouracil
  • Flutamide
  • Fulvestrant
  • Gemcitabine
  • Gemtuzumab ozogamicin
  • Goserelin
  • Histrelin
  • Hydroxyurea
  • Idarubicin
  • Ifosfamide
  • Imatinib
  • Irinotecan
  • Ixazomib
  • Ixabepilone
  • Agents
  • Letrozole
  • Leuprolide
  • Lomustine
  • Mechlorethamine
  • Megestrol
  • Melphalan
  • Mercaptopurine
  • Methotrexate
  • Mitomycin
  • Mitotane
  • Mitoxantrone
  • Nelarabine
  • Nilotinib
  • Omacetaxine
  • Oxaliplatin
  • Paclitaxel
  • Panobinostat
  • Pazopanib
  • Pemetrexed
  • Pentostatin
  • Pertuzumab
  • Pipobroman
  • Pomalidomide
  • Ponatinib
  • Pralatrexate
  • Procarbazine
  • Regorafenib
  • Romidepsin
  • Sorafenib
  • Streptozocin
  • Sunitinib
  • Tamoxifen
  • Temozolomide
  • Temsirolimus
  • Teniposide
  • Thioguanine
  • Thiotepa
  • Topotecan
  • Toremifene
  • Trametinib
  • Trifluridine/tipiracil (combination only)
  • Triptorelin 
  • Valrubicin
  • Vandetanib
  • Vemurafenib
  • Vinblastine
  • Vincristine
  • Vinorelbine
  • Vismodegib
  • Vorinostat
  • Ziv-aflibercept