Helpful Insights forPatients and Caregivers
What is Medication Assited Therapy (MAT)?1-2

Medication Assisted Therapy combines medications with substance use counseling and social support for the treatment of substance use disorders. MAT, combined with counseling and therapy, can increase chances of recovering from an addiction.

Key Facts

  • MAT combines medications and therapy to help treat substance use disorders. The goal of MAT is full recovery from an addiction.1-4
  • MAT is commonly used for the treatment of opioid use disorder, including heroin. MAT may also be used to treat alcohol use disorder.1-4
  • MAT may help reduce cravings and prevent withdrawal symptoms.1-4
  • Medications are available in a variety of forms. These include tablets, liquids, and injections.1-4
  • MAT has been shown to increase an individual’s ability to maintain a job. MAT may also increase the chances of staying in treatment.1-4


  1. Connery HS. Medication-assisted treatment of opioid use disorder: review of the evidence and future directions. Harv Rev Psychiatry. 2015;23(2):63-74.
  2. Mattick RP, Breen C, Kimber J, Davoli M. Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence. Cochrane Database Syst Rev. 2006;(3):1-27.
  3. Kampman K, Jarvis M. American Society of Addiction Medicine (ASAM) National Practice Guideline for the Use of Medications in the Treatment of Addiction Involving Opioid Use. J Addict Med. 2015;9(5):358-67. DOI: 10.1097/ADM.0000000000000166. PubMed PMID: 26406300; PubMed Central PMCID: PMC4605275.
  4. Kleber HD, Weiss RD, Anton RF, Rounsaville BJ, George TP, Strain EC, et al. Treatment of patients with substance use disorders, second edition. American Psychiatic Association. Am J Psychiatry. 2006;163(8 Suppl):5-82. PubMed PMID: 16981488.