epilepsy

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The clinical impact of pharmacogenetics on the treatment of epilepsy.

Löscher W, Klotz U, Zimprich F, Schmidt D. The clinical impact of pharmacogenetics on the treatment of epilepsy. Epilepsia. 2009;50(1):1-23. DOI: 10.1111/j.1528-1167.2008.01716.x. PubMed PMID: 18627414.

Effectiveness of first antiepileptic drug.

Kwan P, Brodie MJ. Effectiveness of first antiepileptic drug. Epilepsia. 2001;42(10):1255-60. PubMed PMID: 11737159.

Pharmacogenomics and epilepsy: the road ahead.

Cavalleri GL, McCormack M, Alhusaini S, Chaila E, Delanty N. Pharmacogenomics and epilepsy: the road ahead. Pharmacogenomics. 2011;12(10):1429-47. DOI: 10.2217/pgs.11.85. PubMed PMID: 22008048.

Personalized medicine approaches in epilepsy.

Walker LE, Mirza N, Yip VLM, Marson AG, Pirmohamed M. Personalized medicine approaches in epilepsy. J Intern Med. 2015;277(2):218-34. DOI: 10.1111/joim.12322. PubMed PMID: 25338670.

Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study.

Ebid A-HIM, Ahmed MMM, Mohammed SA. Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study. Ther Drug Monit. 2007;29(3):305-12. DOI: 10.1097/FTD.0b013e318067ce90. PubMed PMID: 17529887.

Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin.

Tate SK, Depondt C, Sisodiya SM, Cavalleri GL, Schorge S, Soranzo N, et al. Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proc Natl Acad Sci U S A. 2005;102(15):5507-12. DOI: 10.1073/pnas.0407346102. PubMed PMID: 15805193.

Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.

Grover S, Bala K, Sharma S, Gourie-Devi M, Baghel R, Kaur H, et al. Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients. Biochimie. 2010;92(9):1207-12. DOI: 10.1016/j.biochi.2010.04.008. PubMed PMID: 20417680.

Association of polymorphisms in EPHX1, UGT2B7, ABCB1, ABCC2, SCN1A and SCN2A genes with carbamazepine therapy optimization.

Hung C-C, Chang W-L, Ho J-L, Tai JJ, Hsieh T-J, Huang H-C, et al. Association of polymorphisms in EPHX1, UGT2B7, ABCB1, ABCC2, SCN1A and SCN2A genes with carbamazepine therapy optimization. Pharmacogenomics. 2012;13(2):159-69. DOI: 10.2217/pgs.11.141. PubMed PMID: 22188362.

ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients.

Seo T, Ishitsu T, Ueda N, Nakada N, Yurube K, Ueda K, et al. ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients. Pharmacogenomics. 2006;7(4):551-61. DOI: 10.2217/14622416.7.4.551. PubMed PMID: 16753003.

Gene-wide tagging study of the association between ABCC2, ABCC5 and ABCG2 genetic polymorphisms and multidrug resistance in epilepsy.

Kwan P, Wong V, Ng PW, Lui CHT, Sin NC, Wong KS, et al. Gene-wide tagging study of the association between ABCC2, ABCC5 and ABCG2 genetic polymorphisms and multidrug resistance in epilepsy. Pharmacogenomics. 2011;12(3):319-25. DOI: 10.2217/pgs.10.183. PubMed PMID: 21449672.
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