Antipsychotics, like all medications, are associated with adverse effects. To ensure their safe use, clinicians should adhere to conscious monitoring of these adverse effects. Experts have formulated recommended monitoring parameters to assist with early detection of potential adverse effects.

  • What are some general rules to follow when prescribing antipsychotics?1-2
  • Which vitals, labs, and screenings should be ordered for patients receiving antipsychotics and how frequently?3-6
  • Can pharmacists assist with metabolic monitoring for patients receiving antipsychotics?7
  • How does a clinician manage comorbid metabolic syndrome disorders in patients with mental illness?8-10

References

  1. APA: Five things physicians and patients should question. 2013. [Weblink]
  2. Toolbox: Metabolic Adverse Effects of Atypical Antipsychotics. Ment Health Clin. 2013;3(3):115-118. DOI: 10.9740/mhc.n166834.
  3. Consensus development conference on antipsychotic drugs and obesity and diabetes. J Clin Psychiatry. 2004 Feb;65(2):267-72. [PubMed]
  4. Clinical monitoring and management of the metabolic syndrome in patients receiving atypical antipsychotic medications. Prim Care Diabetes. 2009 Feb;3(1):5-15. [PubMed]
  5. Minimizing Cardiovascular Adverse Effects of Atypical Antipsychotic Drugs in Patients with Schizophrenia. Cardiol Res Pract. 2014; Epub 2014 Feb 4. [PubMed]
  6. Monitoring for Antipsychotic Metabolic Effects in an Inpatient Setting. Ment Health Clin. 2011;1(1):10-12. DOI: 10.9740/mhc.n74806.
  7. Monthei EM and Kutscher EC. Evaluation of lipid and glucose monitoring after implementation of a pharmacist initiated antipsychotic monitoring form. 2012. [Weblink]
  8. Bermudes RA, Keck PE, McElroy SL.  Managing Metabolic Abnormalities in the Psychiatrically Ill: A Clinical Guide for Psychiatrists.  American Psychiatric Publishing 2007.
  9. Dayabandara M, Hanwella R, Ratnatunga S, Seneviratne S, Suraweera C, de Silva V. Antipsychotic-associated weight gain: management strategies and impact on treatment adherence. NDT. 2017;Volume 13:2231- 2241. DOI: 10.2147/NDT.S113099. PubMed PMID: 28883731; PubMed Central PMCID: PMC5574691.
  10. Saldaña SN and Kawsky J. Monitoring and treatment of weight gain in children and adolescents treated with second generation antipsychotics (SGAs). Mental Health Clinician. 2011; 1(1): 3-5. [Weblink]